tag:blogger.com,1999:blog-15582690323508368622024-03-05T06:48:04.211+00:00Tuesday1st UK: SSRI / SNRI Antidepressant Statistical PoliticsUnknownnoreply@blogger.comBlogger16125tag:blogger.com,1999:blog-1558269032350836862.post-69272829227818646452012-05-19T12:30:00.000+01:002012-05-19T12:32:52.512+01:00SSRI, SNRI Total Annual Prescription & Increase Data ~ 2011 Prescription Increase 3.1 Million<div style="text-align: center;">
<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhdUycxWBFQmMdVIBxkjX208CiQkyfGTRjyhndfuLNen4O2M461U090_jp0OAnus0XqzjJ4u_BjFuwV2Kb0OeoUdKeNKYe0FaQT2zJcbfL5O1_RXEA2FWVw9WzUzIEufcqDQ_Rn1XI8r1zX/s1600/12+-+1+-+1998+2011+-+SSRI+SNRI+Totals.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="251" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhdUycxWBFQmMdVIBxkjX208CiQkyfGTRjyhndfuLNen4O2M461U090_jp0OAnus0XqzjJ4u_BjFuwV2Kb0OeoUdKeNKYe0FaQT2zJcbfL5O1_RXEA2FWVw9WzUzIEufcqDQ_Rn1XI8r1zX/s400/12+-+1+-+1998+2011+-+SSRI+SNRI+Totals.jpg" width="400" /></a></div>
<div style="text-align: left;">
<a href="http://www.statistics.gov.uk/hub/index.html"><span style="font-size: xx-small;">Reference: UK National Statistics</span></a></div>Unknownnoreply@blogger.com1tag:blogger.com,1999:blog-1558269032350836862.post-12984340132257040652011-05-17T18:25:00.000+01:002011-05-17T18:25:24.870+01:00SSRI, SNRI Total Annual Prescription & Increase Data ~ 2.88 Million Prescription Increase in 2010<div class="separator" style="clear: both; text-align: center;"><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEi1Mm_juSpPyAWjWeYNUCVGouRS3rM6wPIefrnr8EHEBTU8jBZe8jtHhGVfkBln6cD-1KdKXL9wvXKKtn_GmzqzSf5bQZTD3Q2A2RPO6w8fqcwrswdW0dCnkP_XphhH-J9H81YSHFaHWEuS/s1600/2010+-+Chart+1+-+SSRI+SNRI+Totals.JPG" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="207" j8="true" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEi1Mm_juSpPyAWjWeYNUCVGouRS3rM6wPIefrnr8EHEBTU8jBZe8jtHhGVfkBln6cD-1KdKXL9wvXKKtn_GmzqzSf5bQZTD3Q2A2RPO6w8fqcwrswdW0dCnkP_XphhH-J9H81YSHFaHWEuS/s320/2010+-+Chart+1+-+SSRI+SNRI+Totals.JPG" width="320" /></a></div>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1558269032350836862.post-25947608520432325122010-07-21T10:59:00.013+01:002011-02-12T15:41:07.906+00:00SSRI, SNRI - 2009 Annual Total Prescription Increases Hit Record High - 2.54 million<div align="center"></div><div class="separator" style="clear: both; text-align: center;"><img height="231" src="http://farm5.static.flickr.com/4143/4801394248_85c742e7a5_b.jpg" width="400" /></div>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1558269032350836862.post-80340560635584954622010-01-31T23:16:00.009+00:002010-02-05T12:30:13.857+00:00Concerns over the Seroxat Group Litigation<span style="color: #444444;">Due to a situation </span><a href="http://tuesday1st.blogspot.com/2009/05/doh-1998-2008-england-ssri-snri_07.html#comments"><span style="color: #444444;">here</span></a><span style="color: #444444;"> and <a href="http://tuesday1st-mhra-ppes-correspondence.blogspot.com/2009/07/attachment-dear-mr-gregor-as-mr-bob.html"><span style="color: #444444;">around the internet</span></a>, I have felt unable to <span style="color: black;">progress</span> or use this blog for the purpose it was intended. </span><br />
<br />
<span style="color: #444444;">As a result I’m taking time out from statistics and associated issues - as yet unpublished - to facilitate publishing information appertaining to the UK Seroxat Litigation which, having been in the public domain since it was preannounced in 2001/2, is going to court this year. </span><br />
<br />
<span style="color: #444444;">The information encompasses the UK Government Prescription Cost Analysis (PCA) statistics - although at the time of publication of this blog - I was unaware of one significant fact and therefore revelations were unintentional.</span><br />
<br />
<span style="color: #444444;">However, a few weeks after its publication, on first sight of the </span><a href="http://www.hmcourts-service.gov.uk/cms/150_14671.htm"><span style="color: #444444;">Seroxat Group Litigation Order no: 68</span></a><span style="color: #444444;"> it became glaringly obvious that inadvertently, <a href="http://tuesday1st.blogspot.com/2009/05/doh-1998-2008-england-ssri-snri_2963.html"><span style="color: #444444;">the statistics</span></a> – not me – undermine the Litigation.</span><br />
<br />
<span style="color: #444444;">Since becoming aware of and involved with the SSRI drug forums in 2001, I have spoken out - not against the litigation - but in concern for those involved and anyone taking SSRI, SNRI drugs, especially those choosing to or being swapped without consideration from Seroxat to other drugs in the class including Prozac, Lustral and Efexor.</span><br />
<br />
<span style="color: #444444;">T</span><span style="color: #444444;">he statistics are, unfortunately, not the only jeopardy to the frail legal case being successful - Seroxat has a certain notoriety for being “the worst drug” in the class - but is that notoriety well-substantiated or solely due to outside influences? Do the experts agree? </span><br />
<br />
<span style="color: #444444;">Have the UK population been let down by the government, medicines authorities and the media? </span><br />
<br />
<span style="color: #444444;">The new Seroxat Litigation Blog will hopefully extricate the distinct facts, clarify, assemble and publicise each in context - to let the readers decide for them selves. </span><br />
<br />
<span style="color: #444444;">The new blog content will possibly adversely impact on the few hundred people who have not been culled from the originally quoted 10.000 prospective litigants ...... but the full ramifications of not speaking out will possibly impact on thousands or even millions. </span><br />
<br />
<span style="color: #444444;">I have no conflicting interests. </span><br />
<br />
<span style="color: black; font-family: Georgia, "Times New Roman", serif;"><a href="http://the-uk-seroxat-litigation-chronicles.blogspot.com/"><strong>The UK Seroxat Litigation Chronicles</strong></a></span><span style="color: #444444;"><span style="color: #444444;"> -</span> a work in progress - can be found </span><a href="http://the-uk-seroxat-litigation-chronicles.blogspot.com/"><span style="color: #444444;">here</span></a><span style="color: #444444;"><span style="color: #444444;">.</span> </span>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1558269032350836862.post-29257214532184141792010-01-28T10:54:00.009+00:002011-02-12T15:40:29.530+00:00Total Prescriptions, Increases & Paroxetine - Seroxat<div align="center" class="separator" style="clear: both; text-align: center;"></div><div class="separator" style="border-bottom: medium none; border-left: medium none; border-right: medium none; border-top: medium none; clear: both; text-align: center;"><a href="http://farm5.static.flickr.com/4096/4821358395_d18e5acee1_b.jpg" imageanchor="1" style="margin-left: 1em; margin-right: 1em;"><img border="0" height="242" src="http://farm5.static.flickr.com/4096/4821358395_d18e5acee1_b.jpg" width="400" /></a></div><div class="separator" style="border-bottom: medium none; border-left: medium none; border-right: medium none; border-top: medium none; clear: both; text-align: left;"><br />
</div><div class="separator" style="border-bottom: medium none; border-left: medium none; border-right: medium none; border-top: medium none; clear: both; text-align: left;">Paroxetine Seroxat Paxil Aropax Pondera Paroxat Deroxat Cebrilin </div>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1558269032350836862.post-5852058977560081892009-05-07T22:44:00.005+01:002010-01-25T18:03:30.194+00:00SSRI / SNRI: Statistic Graphs: 1998 to 2008UK Department of Health, Prescription Cost Analysis (PCA) Statistics for England, 1998 to 2008 transposed to graph form.Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1558269032350836862.post-87344971631586239972009-05-07T22:41:00.002+01:002010-01-28T10:33:07.549+00:00Prescriptions & Annual Increases<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEg03SlvuZfZBR_C8NhMhGA6tnunto2VFGWypdaY_fBWs2HOw836UZYfHX5drCcJ4K1QibJVcBrdfyvkiblTn0jrW9l79266tef3SwOTjQjAzofDm6JbrV5YmsE_NmH3ntVdAT82BYevAbB4/s1600-h/2+-+P.jpg"><img alt="" border="0" id="BLOGGER_PHOTO_ID_5333200494851700946" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEg03SlvuZfZBR_C8NhMhGA6tnunto2VFGWypdaY_fBWs2HOw836UZYfHX5drCcJ4K1QibJVcBrdfyvkiblTn0jrW9l79266tef3SwOTjQjAzofDm6JbrV5YmsE_NmH3ntVdAT82BYevAbB4/s400/2+-+P.jpg" style="cursor: hand; display: block; height: 230px; margin: 0px auto 10px; text-align: center; width: 400px;" /></a><span style="font-size: 85%;">Click image to enlarge</span><br />
<a href="http://farm4.static.flickr.com/3337/3492596460_045aef0c28_o.jpg"><span style="font-size: 78%;">http://farm4.static.flickr.com/3337/3492596460_045aef0c28_o.jpg</span></a><br />
<span style="font-size: 78%;"><br />
</span>1998 total prescriptions for the SSRI / SNRI drug class were 8,27 Million, in 2008 total prescriptions for just one of the drug class, Citalopram / Cipramil, were over 8.99 Million.<br />
<span style="font-size: 78%;"></span><br />
<span style="font-size: 78%;"><br />
</span><span style="font-size: 78%;">****<br />
Data collection reference:<br />
Department of Health; NHS; Prescription Cost Analysis (PCA) - England.<br />
1998 to 2007:<br />
</span><a href="http://www.dh.gov.uk/en/PublicationsAndStatistics/Statistics/StatisticalWorkAreas/StatisticalHealthCare/DH_4086488"><span style="font-size: 78%;">http://www.dh.gov.uk/en/PublicationsAndStatistics/Statistics/StatisticalWorkAreas/StatisticalHealthCare/DH_4086488</span></a><br />
<span style="font-size: 78%;">2008:<br />
</span><a href="http://www.ic.nhs.uk/webfiles/publications/PCA%202008/PCA%202008.pdf"><span style="font-size: 78%;">http://www.ic.nhs.uk/webfiles/publications/PCA%202008/PCA%202008.pdf</span></a><br />
<span style="font-size: 78%;">P–2 Tuesday<br />
</span><br />
<span style="font-size: 78%;"></span>Unknownnoreply@blogger.com1tag:blogger.com,1999:blog-1558269032350836862.post-79067422879684959832009-05-07T22:33:00.001+01:002010-01-23T12:49:18.031+00:00Totals, Prescriptions & Increases<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhrM22T8iPfjNFdEMTjRkzWfCmHEAs2xACqYym_F1d7hagmejekXjtM96TQo_ZPVfVvFOf8wK4SKp9ggSJ3OR8m9PKDhxd6tu-zVAEl31im3kQ8JP9jU-NWIafYGmg0mgHDAHb84y0Rid6D/s1600-h/1+-+P.jpg"><img alt="" border="0" id="BLOGGER_PHOTO_ID_5333198636094263330" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhrM22T8iPfjNFdEMTjRkzWfCmHEAs2xACqYym_F1d7hagmejekXjtM96TQo_ZPVfVvFOf8wK4SKp9ggSJ3OR8m9PKDhxd6tu-zVAEl31im3kQ8JP9jU-NWIafYGmg0mgHDAHb84y0Rid6D/s400/1+-+P.jpg" style="cursor: hand; display: block; height: 265px; margin: 0px auto 10px; text-align: center; width: 400px;" /></a><span style="font-size: 85%;">Click image to enlarge</span><br />
<a href="http://farm4.static.flickr.com/3591/3492594974_74196089f1_o.jpg"><span style="font-size: 78%;">http://farm4.static.flickr.com/3591/3492594974_74196089f1_o.jpg</span></a><br />
<br />
1998 to 2008 the total median increase in SSRI / SNRIs prescriptions was over 1.61 Million.<br />
<span style="font-size: 78%;"><br />
<br />
****<br />
Data collection reference:<br />
Department of Health; NHS; Prescription Cost Analysis (PCA) - England.<br />
1998 to 2007:<br />
</span><a href="http://www.dh.gov.uk/en/PublicationsAndStatistics/Statistics/StatisticalWorkAreas/StatisticalHealthCare/DH_4086488"><span style="font-size: 78%;">http://www.dh.gov.uk/en/PublicationsAndStatistics/Statistics/StatisticalWorkAreas/StatisticalHealthCare/DH_4086488</span></a><br />
<span style="font-size: 78%;">2008:<br />
</span><a href="http://www.ic.nhs.uk/webfiles/publications/PCA%202008/PCA%202008.pdf"><span style="font-size: 78%;">http://www.ic.nhs.uk/webfiles/publications/PCA%202008/PCA%202008.pdf</span></a><br />
<span style="font-size: 78%;">P–1 Tuesday<br />
<br />
</span><br />
<div></div>Unknownnoreply@blogger.com1tag:blogger.com,1999:blog-1558269032350836862.post-79990188154472887672009-05-07T22:28:00.001+01:002010-01-23T12:48:40.526+00:00Prescription & Increase Totals<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEg7yyjTUbmVN_sNJCKcAK-kcGX99dsrL9n4o_Lev3kGR6jOfBUXLmuaUwImJbp35kwpq_DYIGfVfHfWUmZfh_2HjPpjNHVcijNJlx5JEE9w2hRHnJ7-k727PZ43OM5WgrMo9LZzqpsbvD7u/s1600-h/3+-+P.jpg"><img alt="" border="0" id="BLOGGER_PHOTO_ID_5333197390187681698" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEg7yyjTUbmVN_sNJCKcAK-kcGX99dsrL9n4o_Lev3kGR6jOfBUXLmuaUwImJbp35kwpq_DYIGfVfHfWUmZfh_2HjPpjNHVcijNJlx5JEE9w2hRHnJ7-k727PZ43OM5WgrMo9LZzqpsbvD7u/s400/3+-+P.jpg" style="cursor: hand; display: block; height: 215px; margin: 0px auto 10px; text-align: center; width: 400px;" /></a><span style="font-size: 85%;">Click image to enlarge</span><br />
<a href="http://farm4.static.flickr.com/3331/3492055975_b1ef73c293_o.jpg"><span style="font-size: 78%;">http://farm4.static.flickr.com/3331/3492055975_b1ef73c293_o.jpg</span></a><br />
<span style="font-size: 78%;"><br />
</span>The obvious 2004 to 2005 marginal trends reversal of Total Annual Prescription Increases correlates with: -<br />
<span style="font-size: 78%;"><br />
</span>1 The “Report of the CSM Expert Working Group on the Safety of Selective Serotonin Reuptake Inhibitors (SSRIs)” published December 2004<br />
<a href="http://www.mhra.gov.uk/home/groups/pl-p/documents/drugsafetymessage/con019472.pdf"><span style="font-size: 78%;">http://www.mhra.gov.uk/home/groups/pl-p/documents/drugsafetymessage/con019472.pdf</span></a><br />
<span style="font-size: 78%;"><br />
</span>2 The "House of Commons, Health Committee’s examination into The Influence of the Pharmaceutical Industry" - initiated June 2004 - report published April 5th 2005<br />
<a href="http://www.publications.parliament.uk/pa/cm200405/cmselect/cmhealth/42/42.pdf"><span style="font-size: 78%;">http://www.publications.parliament.uk/pa/cm200405/cmselect/cmhealth/42/42.pdf</span></a><br />
<span style="font-size: 78%;"><br />
<br />
****<br />
Data collection reference:<br />
Department of Health; NHS; Prescription Cost Analysis (PCA) - England.<br />
1998 to 2007:<br />
</span><a href="http://www.dh.gov.uk/en/PublicationsAndStatistics/Statistics/StatisticalWorkAreas/StatisticalHealthCare/DH_4086488"><span style="font-size: 78%;">http://www.dh.gov.uk/en/PublicationsAndStatistics/Statistics/StatisticalWorkAreas/StatisticalHealthCare/DH_4086488</span></a><br />
<span style="font-size: 78%;">2008:<br />
</span><a href="http://www.ic.nhs.uk/webfiles/publications/PCA%202008/PCA%202008.pdf"><span style="font-size: 78%;">http://www.ic.nhs.uk/webfiles/publications/PCA%202008/PCA%202008.pdf</span></a><br />
<span style="font-size: 78%;">P-3 Tuesday<br />
<br />
</span><br />
<div><span style="font-size: 78%;"></span><br />
</div>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1558269032350836862.post-48834474939561573462009-05-07T22:24:00.001+01:002010-01-23T12:47:58.591+00:00Prescribing Trend Decreases from 2004<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhOt8sI0S_gAKlEEQ7-GI8Aeu2k3X5nKP_fXnPnPPVjpdnQu7wU-xEmvs_TZgSM9HMuNpXdn4-XIgCTeX2M3v41GhYJkUrh8D4-xnkjySgWq4c6jo6npzDuvenH9dCrPnpITrvw71hxr4XN/s1600-h/11+-+P-04.jpg"><img alt="" border="0" id="BLOGGER_PHOTO_ID_5333196267915144850" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhOt8sI0S_gAKlEEQ7-GI8Aeu2k3X5nKP_fXnPnPPVjpdnQu7wU-xEmvs_TZgSM9HMuNpXdn4-XIgCTeX2M3v41GhYJkUrh8D4-xnkjySgWq4c6jo6npzDuvenH9dCrPnpITrvw71hxr4XN/s400/11+-+P-04.jpg" style="cursor: hand; display: block; height: 213px; margin: 0px auto 10px; text-align: center; width: 400px;" /></a><span style="font-size: 85%;">Click image to enlarge<br />
</span><a href="http://farm4.static.flickr.com/3353/3492063913_e42dddd151_o.jpg"><span style="font-size: 78%;">http://farm4.static.flickr.com/3353/3492063913_e42dddd151_o.jpg</span></a><br />
<br />
The obvious sharp marginal trend reversal of Venlafaxine Total Prescriptions in 2004 to 2006 correlates with: -<br />
<span style="font-size: 78%;"></span><br />
1 The “Report of the CSM Expert Working Group on the Safety of Selective Serotonin Reuptake Inhibitors (SSRIs)” published December 2004; which single out Venlafaxine for its potential for cardiotoxicity and toxicity in overdose.<br />
<a href="http://www.mhra.gov.uk/home/groups/pl-p/documents/drugsafetymessage/con019472.pdf"><span style="font-size: 78%;">http://www.mhra.gov.uk/home/groups/pl-p/documents/drugsafetymessage/con019472.pdf</span></a><br />
<br />
2 “NICE Clinical Guidelines 23: Depression” published December 2004, issued new guidelines for treatment with Venlafaxine; 1.5.2.16 restricting treatment initiation to specialist mental health medical practitioners and in 1.5.2.17 reinforcing that venlafaxine treatment should only be managed under supervision of specialist mental health medical practitioners.<br />
<a href="http://www.bpd-mind.fsnet.co.uk/NICE_Depression.pdf"><span style="font-size: 78%;">http://www.bpd-mind.fsnet.co.uk/NICE_Depression.pdf</span></a><br />
<span style="font-size: 78%;"></span><br />
Both 1.5.2.16 and 1.5.2.17 recommendations were surreptitiously deleted from the revised prescribing advice issued 31 May 2006 at which point increasing venlafaxine prescription trends resumed.<br />
<a href="http://www.nice.org.uk/nicemedia/pdf/CG23fullguideline.pdf"><span style="font-size: 78%;">http://www.nice.org.uk/nicemedia/pdf/CG23fullguideline.pdf</span></a><br />
<span style="font-size: 78%;"><br />
<br />
****<br />
Data collection reference:<br />
Department of Health; NHS; Prescription Cost Analysis (PCA) - England.<br />
1998 to 2007:<br />
</span><a href="http://www.dh.gov.uk/en/PublicationsAndStatistics/Statistics/StatisticalWorkAreas/StatisticalHealthCare/DH_4086488"><span style="font-size: 78%;">http://www.dh.gov.uk/en/PublicationsAndStatistics/Statistics/StatisticalWorkAreas/StatisticalHealthCare/DH_4086488</span></a><br />
<span style="font-size: 78%;">2008:<br />
</span><a href="http://www.ic.nhs.uk/webfiles/publications/PCA%202008/PCA%202008.pdf"><span style="font-size: 78%;">http://www.ic.nhs.uk/webfiles/publications/PCA%202008/PCA%202008.pdf</span></a><br />
<span style="font-size: 78%;">11-P-04 Tuesday<br />
</span><br />
<div></div>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1558269032350836862.post-39835910825797005862009-05-07T22:15:00.002+01:002010-01-23T12:43:21.006+00:00Prescribing Trends Shift from Paroxetine 2001<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiD09jPkHPhCvlt-Y13vLG2Xnv7f6i9LwUqNneBUhp64UmLhymdckGNfKejJyT5MXl9wORsYO6A0lWR0iyUxf3HOHbEsf-27eQbtDmFU4nbFLgwPD6z-8xKEYhJPEvoDE_F3iR_WWV6Kyxo/s1600-h/12+-+P-01-p.jpg"><img alt="" border="0" id="BLOGGER_PHOTO_ID_5333193913469203554" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiD09jPkHPhCvlt-Y13vLG2Xnv7f6i9LwUqNneBUhp64UmLhymdckGNfKejJyT5MXl9wORsYO6A0lWR0iyUxf3HOHbEsf-27eQbtDmFU4nbFLgwPD6z-8xKEYhJPEvoDE_F3iR_WWV6Kyxo/s400/12+-+P-01-p.jpg" style="cursor: hand; display: block; height: 231px; margin: 0px auto 10px; text-align: center; width: 400px;" /></a><span style="font-size: 85%;">Click image to enlarge</span><br />
<a href="http://farm4.static.flickr.com/3640/3492881456_528c138c6a_o.jpg"><span style="font-size: 78%;">http://farm4.static.flickr.com/3640/3492881456_528c138c6a_o.jpg</span></a><br />
<span style="font-size: 78%;"><br />
</span>The marginal trend reversal of Paroxetine Total Prescriptions in 2001 correlates with: -<br />
<span style="font-size: 78%;"></span><br />
1 USA – August 2001, Paxil (Paroxetine / Seroxat) GSK class action Lawsuit filed in California Superior Court, LA County, USA.<br />
<a href="http://www.onlinelawyersource.com/paxil/class-action.html"><span style="font-size: 78%;">http://www.onlinelawyersource.com/paxil/class-action.html</span></a><br />
<span style="font-size: 78%;"></span><br />
2 UK - The Guardian, December 10, 2001 article “Anti-depressant 'addicts' threaten legal Case”, publicises that solicitors Graham Ross of Ross & Co, Wirral, and Mark Harvey of Hugh James Ford Simey, Cardiff (Now Hugh James) who had liaised with American lawyers about Paxil are investigating the possibility of a UK Seroxat class action.<br />
<a href="http://www.guardian.co.uk/uk/2001/dec/10/medicalscience.highereducation"><span style="font-size: 78%;">http://www.guardian.co.uk/uk/2001/dec/10/medicalscience.highereducation</span></a><br />
<span style="font-size: 78%;"><br />
</span>The increase in the marginal trend reversal of Paroxetine Total Prescriptions in 2002 correlates with: -<br />
<span style="font-size: 78%;"></span><br />
3 UK – The Observer February 3, 2002 article “Hard habit to break”, Mark Harvey, of Hugh James Solicitors, Cardiff; instigates further publicity of the adverse drug reactions (ADRs), side effects and withdrawal problems, connected with the Seroxat --- but common to all drugs in the SSRI / SNRI class.<br />
<a href="http://www.guardian.co.uk/Archive/Article/0,4273,4348653,00.html"><span style="font-size: 78%;">http://www.guardian.co.uk/Archive/Article/0,4273,4348653,00.html</span></a><span style="font-size: 78%;">.<br />
<br />
</span>4 UK - The Observer, Sunday April 28 2002 “The chemistry of happiness“<br />
<a href="http://www.guardian.co.uk/theobserver/2002/apr/28/features.magazine37"><span style="font-size: 78%;">http://www.guardian.co.uk/theobserver/2002/apr/28/features.magazine37</span></a><br />
<br />
5 UK - The November 11th 2002 Parmjit Dhanda Early Day Motion, EDM 238 Seroxat, brought the drug and the SSRI issue to Parliament,<br />
<a href="http://edmi.parliament.uk/EDMi/EDMDetails.aspx?EDMID=24050&SESSION=681"><span style="font-size: 78%;">http://edmi.parliament.uk/EDMi/EDMDetails.aspx?EDMID=24050&SESSION=681</span></a><br />
<span style="font-size: 85%;"><br />
</span>The acceleration of the marginal trend reversal of Paroxetine Total Prescriptions in 2003 correlates to: -<br />
<span style="font-size: 78%;"></span><br />
6 UK - The ensuing parliamentary questions, media coverage and MIND Seroxat Protest, May 12th 2003 at the MHRA London offices, which made national television news coverage<br />
<a href="http://www.mind.org.uk/News+policy+and+campaigns/Press+archive/PRPanoramaSeroxat.htm"><span style="font-size: 78%;">http://www.mind.org.uk/News+policy+and+campaigns/Press+archive/PRPanoramaSeroxat.htm</span></a><br />
<span style="font-size: 78%;"><br />
</span>The Proxetine prescribing trend continues to decline, all be it at a slower rate.<br />
<span style="font-size: 78%;"></span><br />
Significantly, the parliamentary interest and media coverage given to Seroxat and the continuing down trend in Paroxetine prescriptions has had NO impact on the overall marginal trend increases in prescription numbers for the drug class, although ALL are affected by the same ADRs, side effects and withdrawal problems.<br />
<span style="font-size: 78%;"><br />
<br />
****<br />
Data collection reference:<br />
Department of Health; NHS; Prescription Cost Analysis (PCA) - England.<br />
1998 to 2007:<br />
</span><a href="http://www.dh.gov.uk/en/PublicationsAndStatistics/Statistics/StatisticalWorkAreas/StatisticalHealthCare/DH_4086488"><span style="font-size: 78%;">http://www.dh.gov.uk/en/PublicationsAndStatistics/Statistics/StatisticalWorkAreas/StatisticalHealthCare/DH_4086488</span></a><br />
<span style="font-size: 78%;">2008:<br />
</span><a href="http://www.ic.nhs.uk/webfiles/publications/PCA%202008/PCA%202008.pdf"><span style="font-size: 78%;">http://www.ic.nhs.uk/webfiles/publications/PCA%202008/PCA%202008.pdf</span></a><br />
<span style="font-size: 78%;">12-P-01p Tuesday</span><br />
<br />
<div><span style="font-size: 78%;"></span><br />
</div>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1558269032350836862.post-42989676166002050822009-05-07T22:09:00.003+01:002010-01-23T12:55:18.266+00:00Marginal Trends in Prescribing Change 2004 to 2005<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiANehBXJPWw-sqPiU0nei_tsP-gPyCZaiiKk2jVuPgSvS3Zu7N7JA820XXPCffqJrmaDn7t3Iec3wCClAHbF_H2P_1tfWOTN-uev_UUgi1xKR-BYniA9escSD0hIx-GM2jxGKG_IYF4obF/s1600-h/9+-+P-04+1.jpg"><img alt="" border="0" id="BLOGGER_PHOTO_ID_5333192580874238274" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiANehBXJPWw-sqPiU0nei_tsP-gPyCZaiiKk2jVuPgSvS3Zu7N7JA820XXPCffqJrmaDn7t3Iec3wCClAHbF_H2P_1tfWOTN-uev_UUgi1xKR-BYniA9escSD0hIx-GM2jxGKG_IYF4obF/s400/9+-+P-04+1.jpg" style="cursor: hand; display: block; height: 213px; margin: 0px auto 10px; text-align: center; width: 400px;" /></a><span style="font-size: 85%;">Click image to enlarge</span><br />
<a href="http://farm4.static.flickr.com/3328/3498274531_2612922799_o.jpg"><span style="font-size: 78%;">http://farm4.static.flickr.com/3328/3498274531_2612922799_o.jpg</span></a><br />
<span style="font-size: 78%;"><br />
</span>The obvious marginal trend change in Total Prescriptions 2004 to 2006 correlates with: -<br />
<span style="font-size: 78%;"></span><br />
1 The “Report of the CSM Expert Working Group on the Safety of Selective Serotonin Reuptake Inhibitors (SSRIs)” published December 2004 – which found the drug class lacking in safety and efficacy, not notably better than placebo.<br />
<a href="http://www.mhra.gov.uk/home/groups/pl-p/documents/drugsafetymessage/con019472.pdf"><span style="font-size: 78%;">http://www.mhra.gov.uk/home/groups/pl-p/documents/drugsafetymessage/con019472.pdf</span></a><br />
<span style="font-size: 78%;"><br />
</span>2 The "House of Commons, Health Committee’s examination into The Influence of the Pharmaceutical Industry" - initiated June 2004 - report published April 5th 2005.<br />
<a href="http://www.publications.parliament.uk/pa/cm200405/cmselect/cmhealth/42/42.pdf"><span style="font-size: 78%;">http://www.publications.parliament.uk/pa/cm200405/cmselect/cmhealth/42/42.pdf</span></a><br />
<br />
3 “NICE Clinical Guidelines 23: Depression” published December 2004, issued new guidelines for treatment of depression with the introduction of the “Watchful waiting”; 1.4.1.2 a 2 week waiting period for patients with mild depression who did not want an intervention; and in 1.4.1.3 the GP to contact if the 2 week follow-up appointment not kept; and the restricting treatment initiation and management of Venlafaxine; 1.5.2.16 and in 1.5.2.17 to specialist mental health medical practitioners.<br />
<a href="http://www.bpd-mind.fsnet.co.uk/NICE_Depression.pdf"><span style="font-size: 78%;">http://www.bpd-mind.fsnet.co.uk/NICE_Depression.pdf</span></a><br />
<span style="font-size: 78%;"></span><br />
The marginal trend change in Total Prescriptions 2004, caused the anomaly of a Total Prescription Increase of only 402.6 Thousand; the lowest annual SSRI / SNRI drug class increase in prescriptions in the 10 years available statistics.<br />
<span style="font-size: 78%;"></span><br />
Adjusting the median increases in SSRI / SNRIs total prescriptions 1998 to 2008 by removing year 2004 from the equation, increases the median total for 9 of the 10 years from over 1.61 Million per annum to over 1.74 Million.<br />
<span style="font-size: 78%;"></span><br />
<br />
<span style="font-size: 78%;">****<br />
Data collection reference:<br />
Department of Health; NHS; Prescription Cost Analysis (PCA) - England.<br />
1998 to 2007:<br />
</span><a href="http://www.dh.gov.uk/en/PublicationsAndStatistics/Statistics/StatisticalWorkAreas/StatisticalHealthCare/DH_4086488"><span style="font-size: 78%;">http://www.dh.gov.uk/en/PublicationsAndStatistics/Statistics/StatisticalWorkAreas/StatisticalHealthCare/DH_4086488</span></a><br />
<span style="font-size: 78%;">2008:<br />
</span><a href="http://www.ic.nhs.uk/webfiles/publications/PCA%202008/PCA%202008.pdf"><span style="font-size: 78%;">http://www.ic.nhs.uk/webfiles/publications/PCA%202008/PCA%202008.pdf</span></a><br />
<span style="font-size: 78%;">9–P-04 Tuesday<br />
</span><br />
<div></div>Unknownnoreply@blogger.com7tag:blogger.com,1999:blog-1558269032350836862.post-59724727086013177042009-05-07T21:59:00.001+01:002010-01-23T12:33:33.726+00:00Total Drug Net Costs<span style="font-size: 78%;"><img alt="" border="0" id="BLOGGER_PHOTO_ID_5333189923794605794" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEh6wIzx0Muw4G9mZ2BmQwwSFi_EpxVssVZCD79nhltcblEN2EuehbTnOa8BuKKFsGmUi-TEPk7G4dWvi3M2FQ_7ECC2Tw-SH8CApNvOKrSrJIsxGe39T6dzEcVGlfXYFE6iLyF-JIH-xYRk/s400/4+-+C.jpg" style="cursor: hand; display: block; height: 266px; margin: 0px auto 10px; text-align: center; width: 400px;" /></span><br />
<span style="font-size: 85%;">Click image to enlarge</span><br />
<a href="http://farm4.static.flickr.com/3360/3492873728_496fde0913_o.jpg"><span style="font-size: 78%;">http://farm4.static.flickr.com/3360/3492873728_496fde0913_o.jpg</span></a><br />
<br />
1998, total net costs of prescriptions for the SSRI / SNRI drug class were £174,59 Million, these cost peaked in 2004 at £355,44 Million and have subsequently reduced by £159,83 Million to £195,6 Million in 2008.<br />
<span style="font-size: 78%;"><br />
<br />
****<br />
Data collection reference:<br />
Department of Health; NHS; Prescription Cost Analysis (PCA) - England.<br />
1998 to 2007:<br />
</span><a href="http://www.dh.gov.uk/en/PublicationsAndStatistics/Statistics/StatisticalWorkAreas/StatisticalHealthCare/DH_4086488"><span style="font-size: 78%;">http://www.dh.gov.uk/en/PublicationsAndStatistics/Statistics/StatisticalWorkAreas/StatisticalHealthCare/DH_4086488</span></a><br />
<span style="font-size: 78%;">2008:<br />
</span><a href="http://www.ic.nhs.uk/webfiles/publications/PCA%202008/PCA%202008.pdf"><span style="font-size: 78%;">http://www.ic.nhs.uk/webfiles/publications/PCA%202008/PCA%202008.pdf</span></a><br />
<span style="font-size: 78%;">4-C Tuesday</span>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1558269032350836862.post-34911391436764434142009-05-07T21:49:00.001+01:002010-01-23T12:32:45.706+00:00Net Drug Costs Variation<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhsttm8uW1BmgjkmKLbdt2xvybn6JzrzkMJfVIHNKgzWZ1zDvrlcEzBSGIcZa610bhJgOl4AhpuntbPMe1WGfgmXd6r_gY7bw1-48ZiwCZJlbS15XeMdWXHuUlchLD6DLULAwLjtvv8yF0p/s1600-h/10+-+C-04+1.jpg"><img alt="" border="0" id="BLOGGER_PHOTO_ID_5333187286667513586" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhsttm8uW1BmgjkmKLbdt2xvybn6JzrzkMJfVIHNKgzWZ1zDvrlcEzBSGIcZa610bhJgOl4AhpuntbPMe1WGfgmXd6r_gY7bw1-48ZiwCZJlbS15XeMdWXHuUlchLD6DLULAwLjtvv8yF0p/s400/10+-+C-04+1.jpg" style="cursor: hand; display: block; height: 214px; margin: 0px auto 10px; text-align: center; width: 400px;" /></a><span style="font-size: 85%;">Click image to enlarge<br />
</span><a href="http://farm4.static.flickr.com/3596/3510317298_68b3f57c16_o.jpg"><span style="font-size: 78%;">http://farm4.static.flickr.com/3596/3510317298_68b3f57c16_o.jpg</span></a><br />
<span style="font-size: 78%;"><br />
</span>The obvious 2004 to 2005 marginal trends reversal of Total Annual Net Costs for SSRI / SNRI Prescriptions correlates with: -<br />
<br />
1 The “Report of the CSM Expert Working Group on the Safety of Selective Serotonin Reuptake Inhibitors (SSRIs)” published December 2004<br />
<a href="http://www.mhra.gov.uk/home/groups/pl-p/documents/drugsafetymessage/con019472.pdf"><span style="font-size: 78%;">http://www.mhra.gov.uk/home/groups/pl-p/documents/drugsafetymessage/con019472.pdf</span></a><br />
<span style="font-size: 78%;"><br />
</span>2 The "House of Commons, Health Committee’s examination into The Influence of the Pharmaceutical Industry" - initiated June 2004 - report published April 5th 2005<br />
<a href="http://www.publications.parliament.uk/pa/cm200405/cmselect/cmhealth/42/42.pdf">http://www.publications.parliament.uk/pa/cm200405/cmselect/cmhealth/42/42.pdf</a><br />
<span style="font-size: 78%;"></span><br />
<span style="font-size: 78%;"><br />
****<br />
Data collection reference:<br />
Department of Health; NHS; Prescription Cost Analysis (PCA) - England.<br />
1998 to 2007:<br />
</span><a href="http://www.dh.gov.uk/en/PublicationsAndStatistics/Statistics/StatisticalWorkAreas/StatisticalHealthCare/DH_4086488"><span style="font-size: 78%;">http://www.dh.gov.uk/en/PublicationsAndStatistics/Statistics/StatisticalWorkAreas/StatisticalHealthCare/DH_4086488</span></a><br />
<span style="font-size: 78%;">2008:<br />
</span><a href="http://www.ic.nhs.uk/webfiles/publications/PCA%202008/PCA%202008.pdf"><span style="font-size: 78%;">http://www.ic.nhs.uk/webfiles/publications/PCA%202008/PCA%202008.pdf</span></a><br />
<span style="font-size: 78%;">10–C-04 1 Tuesday<br />
</span><br />
<div></div>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1558269032350836862.post-61106914323652124542009-05-07T21:43:00.001+01:002010-01-23T12:31:33.934+00:00Prescription & Net Drug Cost Totals<img alt="" border="0" id="BLOGGER_PHOTO_ID_5333185829036788210" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhUMoyn6lpdGU-iapcpWVEsx65HgtIjBB_bZG0eRKOCF2FNRKSoZC4ij7RR5Nz1RkcN5ZWGvcTkBhZOzxpIEaIV1GGFFxpnHFae4y9Vt_Q0UwAlKHMfIezqkReovOY1t7yYVo9sCgRpA58F/s400/7+-+PC.jpg" style="cursor: hand; display: block; height: 214px; margin: 0px auto 10px; text-align: center; width: 400px;" /><span style="font-size: 85%;">Click image to enlarge<br />
</span><a href="http://farm4.static.flickr.com/3548/3492877450_5e6fe93c12_o.jpg"><span style="font-size: 78%;">http://farm4.static.flickr.com/3548/3492877450_5e6fe93c12_o.jpg</span></a><br />
<span style="font-size: 78%;"></span><br />
In the 10 years of available statistics, the 2008 SSRI / SNRI Total Annual Net Costs of £195.6 Million were the lowest since 1998, when Total Net Costs were £174,59 Million.<br />
<span style="font-size: 78%;"><br />
</span>In 2008 £159,83 Million less cost, brought 16,1 Million more prescriptions than in 1998, when Total Prescription were 8,27 Million.<br />
<span style="font-size: 78%;"></span><br />
<span style="font-size: 78%;"></span><br />
<span style="font-size: 78%;">****<br />
Data collection reference:<br />
Department of Health; NHS; Prescription Cost Analysis (PCA) - England.<br />
1998 to 2007:<br />
</span><a href="http://www.dh.gov.uk/en/PublicationsAndStatistics/Statistics/StatisticalWorkAreas/StatisticalHealthCare/DH_4086488"><span style="font-size: 78%;">http://www.dh.gov.uk/en/PublicationsAndStatistics/Statistics/StatisticalWorkAreas/StatisticalHealthCare/DH_4086488</span></a><br />
<span style="font-size: 78%;">2008:<br />
</span><a href="http://www.ic.nhs.uk/webfiles/publications/PCA%202008/PCA%202008.pdf"><span style="font-size: 78%;">http://www.ic.nhs.uk/webfiles/publications/PCA%202008/PCA%202008.pdf</span></a><br />
<span style="font-size: 78%;">7-PC Tuesday<br />
</span><br />
<div></div>Unknownnoreply@blogger.com0tag:blogger.com,1999:blog-1558269032350836862.post-8722346976185735812009-05-07T17:40:00.003+01:002010-01-23T12:53:30.190+00:00Annual Prescriptions, Increases & Net Cost Totals<a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgu0iCZcKiw66XQMi_0aQS4JAVqrLs3aqSnxaConDDRcMxZHKF3UJSCyVGN_XjrmgOl_MirEmnzTTVtElhi2zecRxS2kdiqbBrpFQEv018HJvzzsJZQoWao2JhIvscB8KGsFnwYdu9c0K0h/s1600-h/28+-+8+9+10+x2+header.jpg"><img alt="" border="0" id="BLOGGER_PHOTO_ID_5333142399616967890" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgu0iCZcKiw66XQMi_0aQS4JAVqrLs3aqSnxaConDDRcMxZHKF3UJSCyVGN_XjrmgOl_MirEmnzTTVtElhi2zecRxS2kdiqbBrpFQEv018HJvzzsJZQoWao2JhIvscB8KGsFnwYdu9c0K0h/s400/28+-+8+9+10+x2+header.jpg" style="cursor: hand; display: block; height: 25px; margin: 0px auto 10px; text-align: center; width: 400px;" /></a><a href="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhhcP8GsdMihyphenhyphenYPoRNX0mpkXKGJX2RlPmSgm3VPepoJOs7BKWEYxubrwcZAdC4xe2mlJco5IGr3jkvISc0thQvCvMpwMOaj6FlejnbjYNcqRKP9zK2v6IiQJoWna96a_ErYO0I707r36Pyt/s1600-h/8+-+P+2.jpg"><img alt="" border="0" id="BLOGGER_PHOTO_ID_5333141179072448594" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhhcP8GsdMihyphenhyphenYPoRNX0mpkXKGJX2RlPmSgm3VPepoJOs7BKWEYxubrwcZAdC4xe2mlJco5IGr3jkvISc0thQvCvMpwMOaj6FlejnbjYNcqRKP9zK2v6IiQJoWna96a_ErYO0I707r36Pyt/s400/8+-+P+2.jpg" style="cursor: hand; display: block; height: 175px; margin: 0px auto 10px; text-align: center; width: 400px;" /></a><img alt="" border="0" id="BLOGGER_PHOTO_ID_5333141785814857122" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEieeQUAaP25W-DPKVFBdEhe9cRZK50Im6y4TtvljDPrQqoNZWUFF7fdvlApjaJHL9v0qCpRS6qleVSbCXgaPBryuhs03ySAPiVgngqwNinwdJ2IzRQC8L60LbZleB5ncYD1JGGsbUP-_97b/s400/9+-+P-04+2.jpg" style="cursor: hand; display: block; height: 175px; margin: 0px auto 10px; text-align: center; width: 400px;" /><img alt="" border="0" id="BLOGGER_PHOTO_ID_5333142211911670274" src="https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEhZP1ifUOao_ol8GKJquiS7uM0sZRhLELZIDQ38J932ufHzEnmWK0Q_QZVMFbdDsGq7suhcuWY811vjmN0hueVcbHQhDGKYKisdLzKjHu4nH2lLjvwJXhmY6xC5cs9Hm2Z1vQRY6Qyp_GVE/s400/10+-+C-04+2.jpg" style="cursor: hand; display: block; height: 175px; margin: 0px auto 10px; text-align: center; width: 400px;" /> <span style="font-size: 85%;">Click any image to enlarge<br />
</span><br />
<a href="http://farm4.static.flickr.com/3327/3510484082_2cd7df45e1_o.jpg"><span style="font-size: 78%;">http://farm4.static.flickr.com/3327/3510484082_2cd7df45e1_o.jpg</span></a><br />
<span style="font-size: 78%;"><br />
</span><a href="http://farm4.static.flickr.com/3347/3510633522_63041d1702_o.jpg"><span style="font-size: 78%;">http://farm4.static.flickr.com/3347/3510633522_63041d1702_o.jpg</span></a><br />
<span style="font-size: 78%;"><br />
</span><a href="http://farm4.static.flickr.com/3385/3510660774_3dac575f0a_o.jpg"><span style="font-size: 78%;">http://farm4.static.flickr.com/3385/3510660774_3dac575f0a_o.jpg</span></a><br />
<span style="font-size: 78%;"><br />
<br />
****<br />
Data collection reference:<br />
Department of Health; NHS; Prescription Cost Analysis (PCA) - England.<br />
1998 to 2007:<br />
</span><a href="http://www.dh.gov.uk/en/PublicationsAndStatistics/Statistics/StatisticalWorkAreas/StatisticalHealthCare/DH_4086488"><span style="font-size: 78%;">http://www.dh.gov.uk/en/PublicationsAndStatistics/Statistics/StatisticalWorkAreas/StatisticalHealthCare/DH_4086488</span></a><br />
<span style="font-size: 78%;">2008:<br />
</span><a href="http://www.ic.nhs.uk/webfiles/publications/PCA%202008/PCA%202008.pdf"><span style="font-size: 78%;">http://www.ic.nhs.uk/webfiles/publications/PCA%202008/PCA%202008.pdf</span></a><br />
<span style="font-size: 78%;"></span><br />
<div><div><div><div><div><div><div align="left"><span style="font-size: 78%;">8-P 2/9-P-04 2/10-C04 2 Tuesday </span><br />
</div><div align="left"></div></div></div></div></div></div></div>Unknownnoreply@blogger.com1